Showing posts with label CDC scabies. Show all posts
Showing posts with label CDC scabies. Show all posts
Monday, July 25, 2011
SCABIES & RETIREMENTS HOMES
Scabies and retirement homes. We all have to visit some time or another to visit a family member or friend in the retirement home. All to often without us knowing there could be trouble lurking. In this case one that you cannot see! So with that said let us talk about what one can do with these situations! First, take a good look at the person you are visiting. Look closely at their hands, elbows and other areas that have folds of skin. These are the likely areas that will show rashes, red itchy bumps or track marks from Scabies. No one really knows for sure why they are attracted to these areas, but one guess is they can burrow in between the creases like it is a ditch just waiting for them. So before you go and hug someone or offer up a hand of love take some precautions and observe before you give contact. This is not meant to be mean in any way. This is meant to keep you from getting infected with a disease or diseases! If you notice symptoms please notify the Manager about this so the person or persons can get treatment for scabies. I would recommend a followup letter sent regarding this so it does not get shoved under the carpet. These people are helpless and need your assistance in matters like this! Another thought on this is sitting. When you visit often times you take a seat right away to be at their level. Here is a word of advice to this situation! Bring a small folding chair to sit in. You know the history of your chair and certainly not the history of what is going on in the Retirement home. Who knows who sat where and for how long. Scabies is very very contagious and can be contracted with contact to people or things that they have touched. Avoidance is the number one preventer of getting this disease. During your visit, if a worker is present look them over as well. This could be a leading indicator of what is going on while you are not there. Look for signs or indicators on them too! These days money is extremely tight and proposals to reduce income to these enterprises will without doubt cause these firms to reduce oversight and inact shortcuts. These shortcuts can be numerous and have negative impact on the person's health you are seeing. Scabies are prominate at these places so please take care when visiting them so you do not become a statistic. Our position is to assist in the eradication of scabies and spread of this disease and that one day it is eliminated like Polio!
Sunday, July 24, 2011
SCABIES - FIRST CASES OF IVERMECTIN RESISTANCE
First Cases of Ivermectin resistance
Scabies is endemic in many remote Aboriginal communities in
northern Australia. Some of the inhabitants have been treated with over 50 oral
doses of ivermectin over the last 5 years [6]. Clinical and in vitro evidence of ivermectin resistance
has developed in two individuals [6]. No ivermectin-resistant arthropod has previously been reported
to cause human infestation, however, such resistance has been induced in the
laboratory under intense drug exposure with the horn fly [7], fruit fly [8], and a species of tick [9].
From their experience in this endemic population, Currie et al.
now recommend a weekly dosing interval for ivermectin rather than their
previous use of a fortnight between treatments [6]. Additionally, they note that higher doses have been suggested
by some authors [1].
Summary of available treatments for scabies
The standard treatment of scabies has been the application of a
prescription scabicide overnight to the entire body surface. The scalp is
normally excluded with adults, but treatment of this body region is important
in infants. Inasmuch as the mite prefers warm, moist areas, the finger and toe
creases, intergluteal cleft, umbilicus, and skin beneath finger and toe nails
must be treated thoroughly. To reduce the incidence of reinfestation and fomite
transmission, clothing, linens, and towels used within the previous week should
be washed in hot water and dried on high heat. All family members and close
contacts must be treated simultaneously, even if they have not developed
pruritus or other clinical signs of scabies. The relatively common occurrence
of asymptomatic mite carriers is greatly underappreciated.
The antiparasitic agent, ivermectin, has been used for 10 years in
humans for this disease and is slowly gaining prominence because of its high
efficacy, ease of treatment, and low risk of side effects. A summary of the
standard topical therapies with comments are listed in Table 1.
References
1. Burkhart CG, Burkhart CN. An epidemiologic and therapeutic
reassessment of scabies. Cutis 2000;65:233-40. PubMed
2. Arlian LG, Morgan MS, Paul CC. Evidence that scabies mites
(Acari: Sarcoptidae) influence production of interleukin-10 and function of
T-regulatory cells (Tr1) in humans. J Med Entomol 2006:43:283-7. PubMed
3. Arlian LG, Vyszenski-Moher DL, Rapp M, Hull BE. Production of
IL-1α and IL-1β by human skin equivalents parasitized by Sarcoptes scabiei. J
Parasitol 1996;82:719-23. PubMed
4. Arlian LG, Morgan MS, Neal JS. Modulation of cytokine
expression in human keratinocytes and fibroblasts by extracts of scabies mites.
AM J Trop Med Hyg 2003;69:652-6. PubMed
5. Arlian LG, Morgan MS, Neal JS. Extracts of scabies mites
(Sarcoptidae: Sarcoptes scabiei) modulate cytokine expression by human
peripheral blood mononuclear cells and dendritic cells. J Med Entomol
2004;41:69-73. PubMed
6. Currie BJ, Harumal P, McKinnon M, Walton SF. First
documentation of in vivo and in vitro ivermectin resistance in Sarcoptes
scabiei. Clin Infect Dis 2004:39:e8-e12. PubMed
7. Byford RL, Craig ME, DeRouen SM. Influence of permethrin,
diazinon, and ivermectin treatments on insecticide resistance in the horn fly
(Diptera: Muscidae). Int J Parasitol 1999;29:125-35. PubMed
8. Kane NS, Hirschberg B, Qian S. Drug-resistant Drosophila
indicate glutamate-gated chloride channels are targets for the antiparasitics
nodulisporic acid and ivermectin. Proc Natl Acad Sci USA 2000;97:13949-54. PubMed
9. Benavides E, Romero A. Preliminary results of a larval
resistance test to ivermectins using Boophilus microplus reference strains. Ann
NY Acad Sci 2000;916:610-2. PubMed
10. Rapp CM, Morgan MS, Arlian LG. Presence of host
immunoglobulin in the gut of Sarcoptes scabiei (Acari: Sarcoptidae). J Med
Entomol 2006;43:539-42. PubMed
Scabies is endemic in many remote Aboriginal communities in
northern Australia. Some of the inhabitants have been treated with over 50 oral
doses of ivermectin over the last 5 years [6]. Clinical and in vitro evidence of ivermectin resistance
has developed in two individuals [6]. No ivermectin-resistant arthropod has previously been reported
to cause human infestation, however, such resistance has been induced in the
laboratory under intense drug exposure with the horn fly [7], fruit fly [8], and a species of tick [9].
From their experience in this endemic population, Currie et al.
now recommend a weekly dosing interval for ivermectin rather than their
previous use of a fortnight between treatments [6]. Additionally, they note that higher doses have been suggested
by some authors [1].
Summary of available treatments for scabies
The standard treatment of scabies has been the application of a
prescription scabicide overnight to the entire body surface. The scalp is
normally excluded with adults, but treatment of this body region is important
in infants. Inasmuch as the mite prefers warm, moist areas, the finger and toe
creases, intergluteal cleft, umbilicus, and skin beneath finger and toe nails
must be treated thoroughly. To reduce the incidence of reinfestation and fomite
transmission, clothing, linens, and towels used within the previous week should
be washed in hot water and dried on high heat. All family members and close
contacts must be treated simultaneously, even if they have not developed
pruritus or other clinical signs of scabies. The relatively common occurrence
of asymptomatic mite carriers is greatly underappreciated.
The antiparasitic agent, ivermectin, has been used for 10 years in
humans for this disease and is slowly gaining prominence because of its high
efficacy, ease of treatment, and low risk of side effects. A summary of the
standard topical therapies with comments are listed in Table 1.
References
1. Burkhart CG, Burkhart CN. An epidemiologic and therapeutic
reassessment of scabies. Cutis 2000;65:233-40. PubMed
2. Arlian LG, Morgan MS, Paul CC. Evidence that scabies mites
(Acari: Sarcoptidae) influence production of interleukin-10 and function of
T-regulatory cells (Tr1) in humans. J Med Entomol 2006:43:283-7. PubMed
3. Arlian LG, Vyszenski-Moher DL, Rapp M, Hull BE. Production of
IL-1α and IL-1β by human skin equivalents parasitized by Sarcoptes scabiei. J
Parasitol 1996;82:719-23. PubMed
4. Arlian LG, Morgan MS, Neal JS. Modulation of cytokine
expression in human keratinocytes and fibroblasts by extracts of scabies mites.
AM J Trop Med Hyg 2003;69:652-6. PubMed
5. Arlian LG, Morgan MS, Neal JS. Extracts of scabies mites
(Sarcoptidae: Sarcoptes scabiei) modulate cytokine expression by human
peripheral blood mononuclear cells and dendritic cells. J Med Entomol
2004;41:69-73. PubMed
6. Currie BJ, Harumal P, McKinnon M, Walton SF. First
documentation of in vivo and in vitro ivermectin resistance in Sarcoptes
scabiei. Clin Infect Dis 2004:39:e8-e12. PubMed
7. Byford RL, Craig ME, DeRouen SM. Influence of permethrin,
diazinon, and ivermectin treatments on insecticide resistance in the horn fly
(Diptera: Muscidae). Int J Parasitol 1999;29:125-35. PubMed
8. Kane NS, Hirschberg B, Qian S. Drug-resistant Drosophila
indicate glutamate-gated chloride channels are targets for the antiparasitics
nodulisporic acid and ivermectin. Proc Natl Acad Sci USA 2000;97:13949-54. PubMed
9. Benavides E, Romero A. Preliminary results of a larval
resistance test to ivermectins using Boophilus microplus reference strains. Ann
NY Acad Sci 2000;916:610-2. PubMed
10. Rapp CM, Morgan MS, Arlian LG. Presence of host
immunoglobulin in the gut of Sarcoptes scabiei (Acari: Sarcoptidae). J Med
Entomol 2006;43:539-42. PubMed
Wednesday, July 20, 2011
Scabies - Scabie laying eggs in burrow
Here is an image of a scabie laying eggs in a burrow. Note the black dots that surround the eggs. This is feces from the scabie and it also is the cause for people to have skin irrations or rashes. In the other blog posting it was a depiction however in this image this is the real thing! Send us your scabie images so we can show others. For fast results in eradication see www.scabiehelp.com you will glad you bought the easy to use guide. Its cheap for what you get!
Monday, July 11, 2011
DO YOU HAVE SCABIES? ARE YOU TIRED OF BEING MISERABLE? GET RELIEF NOW WITH THE SCABIE HELP E-BOOK
Are you miserable due to the scabies?
Have you been to see many Doctors and still get them back?
There are reasons why this is happening and we address these and many other issues.
Look at the feedback from our satisfied customers. They all have great things to say about their experience in getting rid of the bugs.
Its FREE for a limited time! Get your life back now www.scabiehelp.com
Have you been to see many Doctors and still get them back?
There are reasons why this is happening and we address these and many other issues.
Look at the feedback from our satisfied customers. They all have great things to say about their experience in getting rid of the bugs.
Its FREE for a limited time! Get your life back now www.scabiehelp.com
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